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Hot Topics of the Day are picked by experts to capture the latest information and publications on public health genomics and precision health for various diseases and health topics. Sources include published scientific literature, reviews, blogs and popular press articles.

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29 hot topic(s) found with the query "Kidney cancer"

The blood metabolome of incident kidney cancer: A case–control study nested within the MetKid consortium
F Guida et al, PLOS Medicine, September 21, 2021 (Posted: Sep 21, 2021 9AM)

We looked at the association between kidney cancer and the levels of 1,416 metabolites measured in blood on average 8 years before the disease onset. The study included 1,305 kidney cancer cases and 1,305 healthy controls. We found 25 metabolites robustly associated with kidney cancer risk. Specifically, multiple glycerophospholipids (GPLs) were inversely associated with risk, while several amino acids were positively associated with risk. Accounting for BMI highlighted that some—but not all—metabolites associated with kidney cancer risk are influenced by BMI.

Deep learning for end-to-end kidney cancer diagnosis on multi-phase abdominal computed tomography
KH Uhm et al, NPJ Precision Oncology, June 18, 2021 (Posted: Jun 19, 2021 7AM)

While deep learning has been recently applied to the automated diagnosis of renal tumor, classification of a wide range of subtype classes has not been sufficiently studied yet. In this paper, we propose an end-to-end deep learning model for the differential diagnosis of five major histologic subtypes of renal tumors including both benign and malignant tumors on multi-phase CT.

Prevalence of Germline Mutations in Cancer Susceptibility Genes in Patients With Advanced Renal Cell Carcinoma
MI Carlo et al, JAMA Oncology, July 5, 2018 (Posted: Jul 06, 2018 9AM)

Broadening the View of Germline Mutations in Kidney Cancer
PG Pilie et al, JAMA Oncology, July 5, 2018 (Posted: Jul 06, 2018 9AM)

Advances in the diagnosis of hereditary kidney cancer: Initial results of a multigene panel test
KA Nguyen et al ACS Journal, August 8, 2017 (Posted: Aug 13, 2017 1PM)

Intrinsic Genomic Differences Between African American and White Patients With Clear Cell Renal Cell Carcinoma
B Krishnan et al, JAMA Oncology, March 24, 2016 (Posted: Mar 26, 2016 3PM)

Genetics of Kidney Cancer (Renal Cell Cancer) (PDQ®): Health Professional Version.
PDQ editorial board, NCI< 2016 (Posted: Mar 14, 2016 8AM)

Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma
F, CHen et al, Cell, March 2016 (Posted: Mar 14, 2016 8AM)

FDA Expands Use of Immunotherapeutic to Kidney Cancer
K Honey, AACR Blog Post, November 25, 2015 (Posted: Nov 28, 2015 6PM)

Diagnostic approach to hereditary renal cell carcinoma.
Gupta Shiva et al. AJR. American journal of roentgenology 2015 May (5) 1031-41 (Posted: Nov 04, 2015 6PM)

Renal medullary carcinoma and sickle cell trait: A systematic review.
Alvarez Ofelia et al. Pediatric blood & cancer 2015 Oct (10) 1694-9 (Posted: Nov 04, 2015 6PM)

A clearer view of the molecular complexity of clear cell renal cell carcinoma.
Frew Ian J et al. Annual review of pathology 2015 263-89 (Posted: Nov 04, 2015 6PM)

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma
The Cancer Genome Atlas, NEJM, November 4, 2015 (Posted: Nov 04, 2015 6PM)

NCI Information: The most common type of kidney cancer in adults is renal cell carcinoma
(Posted: Mar 23, 2015 10AM)

Kidney cancer: New genomic variation found.
Stone Louise et al. Nat Rev Urol 2015 Feb (2) 67 (Posted: Mar 23, 2015 9AM)

Expression of lactate/H? symporters MCT1 and MCT4 and their chaperone CD147 predicts tumor progression in clear cell renal cell carcinoma: immunohistochemical and The Cancer Genome Atlas data analyses.
Kim Younghye et al. Hum. Pathol. 2015 Jan (1) 104-12 (Posted: Mar 23, 2015 9AM)

DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinoma.
Lasseigne Brittany N et al. BMC Med 2014 Dec 4. (1) 235 (Posted: Mar 23, 2015 9AM)

Activation of human telomerase reverse transcriptase through gene fusion in clear cell sarcoma of the kidney.
Karlsson Jenny et al. Cancer Lett. 2015 Feb 28. (2) 498-501 (Posted: Mar 23, 2015 9AM)

A Genomic Algorithm for the Molecular Classification of Common Renal Cortical Neoplasms: Development and Validation.
Gowrishankar Banumathy et al. J. Urol. 2014 Dec 11. (Posted: Mar 23, 2015 9AM)

miR-210 Is a Prognostic Marker in Clear Cell Renal Cell Carcinoma.
Samaan Sara et al. J Mol Diagn 2015 Mar (2) 136-44 (Posted: Mar 23, 2015 9AM)

Identification of genes and pathways involved in kidney renal clear cell carcinoma.
Yang William et al. BMC Bioinformatics 2014 S2 (Posted: Mar 23, 2015 9AM)

Integrative genome-wide analysis of the determinants of RNA splicing in kidney renal clear cell carcinoma.
Lehmann Kjong-Van et al. Pac Symp Biocomput 2015 44-55 (Posted: Mar 23, 2015 9AM)

Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution.
Kovac Michal et al. Nat Commun 2015 6336 (Posted: Mar 23, 2015 9AM)

Find out about genetic conditions and tests associated with kidney cancer
from the NIH Genetic Testing Registry Brand (Posted: Mar 23, 2015 9AM)

Urinary Biomarkers for the Detection and Management of Localized Renal Cell Carcinoma
B. Rini et al. JAMA Oncology, March 2015 (Posted: Mar 23, 2015 9AM)

Evaluation of Urine Aquaporin-1 and Perilipin-2 Concentrations as Biomarkers to Screen for Renal Cell CarcinomaA Prospective Cohort Study
J. Morrissey et al. JAMA Oncology, March 2015 (Posted: Mar 23, 2015 9AM)

Kidney (Renal Cell) Cancer—Patient Version
Brand (Posted: Jan 11, 2014 11AM)

There are two kidneys, one on each side of the spine, above the waist. The kidneys clean the blood to take out waste and make urine. Urine collects in the renal pelvis, the area at the center of the kidney, and then passes through the ureter, into the bladder, and out of the body. The kidneys also make hormones that help control blood pressure and signal the bone marrow to make red blood cells when needed. There are three main types of kidney cancer. Renal cell cancer is the most common type in adults and Wilms tumors are the most common in children. These types form in the tissues of the kidney that make urine. Transitional cell cancer forms in the renal pelvis and ureter in adults. Smoking and taking certain pain medicines for a long time can increase the risk of adult kidney cancer. Certain inherited disorders can increase the risk of kidney cancer in children and adults. These include von Hippel-Lindau syndrome, hereditary leiomyomatosis and renal cell cancer, Birt-Hogg-Dubé syndrome, and hereditary papillary renal cancer. Kidney tumors may be benign or malignant. Cancer

CDC Information: What is kidney cancer? [PDF 40.33 KB]
Brand (Posted: Jan 01, 2014 0AM)

Kidney cancer, childhood
From NCATS Genetic and Rare Diseases Information Center Brand (Posted: Jan 01, 2011 0AM)


Disclaimer: Articles listed in Hot Topics of the Day are selected by Public Health Genomics Branch to provide current awareness of the scientific literature and news. Inclusion in the update does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.
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